Flight Schedules from Knoxville to Des Moines

  • Depart
    Arrive
    Duration
    Flight & AirCraft
    Mo Tu We Th Fr Sa Su
  • 05:45 (TYS)
    06:46 (ATL)
    6h 18m
    DL 5519 (Canadair Regional Jet 900)
    2h 59m layover in Atlanta (ATL)
  • 09:45 (ATL)
    11:03 (DSM)
    6h 18m
    DL 1800 (Boeing 717-200)
  • 06:00 (TYS)
    07:41 (DTW)
    6h 1m
    DL 3932 (Canadair Regional Jet)
    2h 29m layover in Detroit (DTW)
  • 10:10 (DTW)
    11:01 (DSM)
    6h 1m
    DL 4516 (Canadair Regional Jet 900)
  • 06:00 (TYS)
    07:41 (DTW)
    6h 1m
    DL 3515 (Canadair Regional Jet)
    2h 29m layover in Detroit (DTW)
  • 10:10 (DTW)
    11:01 (DSM)
    6h 1m
    DL 3487 (Canadair Regional Jet)
  • 06:00 (TYS)
    07:44 (DTW)
    5h 42m
    DL 3923 (Canadair Regional Jet 900)
    2h 12m layover in Detroit (DTW)
  • 09:56 (DTW)
    10:42 (DSM)
    5h 42m
    DL 4800 (Canadair Regional Jet 900)
  • 06:00 (TYS)
    07:42 (DTW)
    6h 18m
    DL 3691 (Canadair Regional Jet)
    2h 28m layover in Detroit (DTW)
  • 10:10 (DTW)
    11:18 (DSM)
    6h 18m
    DL 3514 (Canadair Regional Jet)
  • 06:29 (TYS)
    07:35 (ATL)
    5h 32m
    DL 3779 (Canadair Regional Jet 900)
    2h 10m layover in Atlanta (ATL)
  • 09:45 (ATL)
    11:01 (DSM)
    5h 32m
    DL 1800 (Boeing 717-200)
  • 06:45 (TYS)
    08:26 (MSP)
    5h 30m
    DL 3818 (Canadair Regional Jet 900)
    1h 34m layover in Minneapolis/St Paul (MSP)
  • 10:00 (MSP)
    11:15 (DSM)
    5h 30m
    DL 4105 (Canadair Regional Jet)
  • 07:00 (TYS)
    08:14 (ATL)
    5h 11m
    DL 3779 (Canadair Regional Jet 900)
    1h 40m layover in Atlanta (ATL)
  • 09:54 (ATL)
    11:11 (DSM)
    5h 11m
    DL 3962 (Canadair Regional Jet 900)
  • 07:01 (TYS)
    07:45 (ORD)
    4h 41m
    AA 3574 (Canadair Regional Jet 700)
    1h 35m layover in Chicago (ORD)
  • 09:20 (ORD)
    10:42 (DSM)
    4h 41m
    UA 558 (Airbus A319)
  • 07:25 (TYS)
    08:10 (ORD)
    3h 59m
    UA 3940 (Embraer RJ 135/140/145)
    50m layover in Chicago (ORD)
  • 09:00 (ORD)
    10:24 (DSM)
    3h 59m
    UA 558 (Boeing 737-800)
  • 07:40 (TYS)
    09:22 (DTW)
    4h 29m
    DL 3870 (Canadair Regional Jet)
    48m layover in Detroit (DTW)
  • 10:10 (DTW)
    11:09 (DSM)
    4h 29m
    DL 3903 (Canadair Regional Jet)
  • 07:40 (TYS)
    09:24 (DTW)
    4h 21m
    DL 4714 (Canadair Regional Jet)
    46m layover in Detroit (DTW)
  • 10:10 (DTW)
    11:01 (DSM)
    4h 21m
    DL 4516 (Canadair Regional Jet 900)
  • 07:40 (TYS)
    09:26 (DTW)
    6h 30m
    DL 3934 (Canadair Regional Jet)
    2h 49m layover in Detroit (DTW)
  • 12:15 (DTW)
    13:10 (DSM)
    6h 30m
    DL 5558 (Canadair Regional Jet 700)
  • 07:48 (TYS)
    09:30 (DTW)
    4h 30m
    DL 3825 (Canadair Regional Jet)
    40m layover in Detroit (DTW)
  • 10:10 (DTW)
    11:18 (DSM)
    4h 30m
    DL 3514 (Canadair Regional Jet)
  • 07:48 (TYS)
    09:30 (DTW)
    4h 30m
    DL 3463 (Canadair Regional Jet)
    40m layover in Detroit (DTW)
  • 10:10 (DTW)
    11:18 (DSM)
    4h 30m
    DL 3448 (Canadair Regional Jet)
  • 08:30 (TYS)
    09:41 (ATL)
    6h 15m
    DL 2849 (Boeing (Douglas) MD-90)
    2h 49m layover in Atlanta (ATL)
  • 12:30 (ATL)
    13:45 (DSM)
    6h 15m
    DL 1800 (Boeing 717-200)
  • 08:45 (TYS)
    10:06 (MSP)
    4h 44m
    DL 4008 (Canadair Regional Jet 900)
    59m layover in Minneapolis/St Paul (MSP)
  • 11:05 (MSP)
    12:29 (DSM)
    4h 44m
    DL 3745 (Canadair Regional Jet)
  • 09:10 (TYS)
    10:00 (ORD)
    5h 20m
    UA 3826 (Embraer RJ 135/140/145)
    2h layover in Chicago (ORD)
  • 12:00 (ORD)
    13:30 (DSM)
    5h 20m
    AA 3181 (Embraer RJ145)
  • 09:20 (TYS)
    11:04 (DTW)
    4h 43m
    DL 4714 (Canadair Regional Jet)
    1h 6m layover in Detroit (DTW)
  • 12:10 (DTW)
    13:03 (DSM)
    4h 43m
    DL 3823 (Canadair Regional Jet)
  • 09:28 (TYS)
    10:28 (ATL)
    5h 29m
    DL 3706 (Canadair Regional Jet 900)
    2h 2m layover in Atlanta (ATL)
  • 12:30 (ATL)
    13:57 (DSM)
    5h 29m
    DL 1800 (Boeing 717-200)
  • 09:40 (TYS)
    10:36 (ATL)
    5h 6m
    DL 2488 (Boeing 717-200)
    1h 54m layover in Atlanta (ATL)
  • 12:30 (ATL)
    13:46 (DSM)
    5h 6m
    DL 5126 (Canadair Regional Jet 900)
  • 09:50 (TYS)
    10:51 (ATL)
    4h 55m
    DL 5528 (Canadair Regional Jet 700)
    1h 39m layover in Atlanta (ATL)
  • 12:30 (ATL)
    13:45 (DSM)
    4h 55m
    DL 1800 (Boeing 717-200)
  • 10:15 (TYS)
    11:17 (ATL)
    4h 29m
    DL 918 (Boeing (Douglas) MD-88)
    1h 13m layover in Atlanta (ATL)
  • 12:30 (ATL)
    13:44 (DSM)
    4h 29m
    DL 1800 (Boeing 717-200)
  • 10:15 (TYS)
    11:00 (ORD)
    5h 27m
    UA 3826 (Embraer RJ 135/140/145)
    2h 20m layover in Chicago (ORD)
  • 13:20 (ORD)
    14:42 (DSM)
    5h 27m
    AA 3583 (Canadair Regional Jet 700)
  • 10:30 (TYS)
    11:36 (ATL)
    4h 22m
    DL 3856 (Canadair Regional Jet 900)
    54m layover in Atlanta (ATL)
  • 12:30 (ATL)
    13:52 (DSM)
    4h 22m
    DL 1800 (Boeing 717-200)
  • 11:05 (TYS)
    12:14 (CLT)
    4h 37m
    AA 5589 (Canadair Regional Jet 900)
    1h 1m layover in Charlotte (CLT)
  • 13:15 (CLT)
    14:42 (DSM)
    4h 37m
    AA 5212 (Canadair Regional Jet 900)
  • 11:43 (TYS)
    12:40 (ORD)
    3h 59m
    AA 3575 (Embraer RJ145)
    40m layover in Chicago (ORD)
  • 13:20 (ORD)
    14:42 (DSM)
    3h 59m
    AA 3583 (Canadair Regional Jet 700)
  • 11:48 (TYS)
    12:49 (ATL)
    5h 32m
    DL 5301 (Canadair Regional Jet)
    2h 15m layover in Atlanta (ATL)
  • 15:04 (ATL)
    16:20 (DSM)
    5h 32m
    DL 5126 (Canadair Regional Jet 900)
  • 12:00 (TYS)
    13:03 (ATL)
    5h 13m
    DL 2157 (Boeing 717-200)
    1h 52m layover in Atlanta (ATL)
  • 14:55 (ATL)
    16:13 (DSM)
    5h 13m
    DL 1532 (Boeing 717-200)
    multiple schedules, see details
    • Valid between 31 Oct 2016 - 18 Dec 2016
    • Valid between 02 Jan 2017 - 05 Mar 2017
      -
  • 12:40 (TYS)
    14:23 (DTW)
    4h 33m
    DL 3835 (Canadair Regional Jet)
    57m layover in Detroit (DTW)
  • 15:20 (DTW)
    16:13 (DSM)
    4h 33m
    DL 3823 (Canadair Regional Jet 900)
  • 12:45 (TYS)
    14:26 (DTW)
    4h 32m
    DL 3964 (Canadair Regional Jet)
    54m layover in Detroit (DTW)
  • 15:20 (DTW)
    16:17 (DSM)
    4h 32m
    DL 4646 (Canadair Regional Jet)
  • 12:45 (TYS)
    14:26 (DTW)
    4h 28m
    DL 3676 (Canadair Regional Jet)
    54m layover in Detroit (DTW)
  • 15:20 (DTW)
    16:13 (DSM)
    4h 28m
    DL 3514 (Canadair Regional Jet)
  • 13:45 (TYS)
    14:34 (ORD)
    4h 18m
    UA 4347 (Embraer RJ 135/140/145)
    1h 16m layover in Chicago (ORD)
  • 15:50 (ORD)
    17:03 (DSM)
    4h 18m
    UA 5950 (Canadair Regional Jet 700)
    multiple schedules, see details
    • Valid between 12 Dec 2016 - 18 Dec 2016
      -
      -
      -
    • Valid between 13 Feb 2017 - 05 Mar 2017
      -
      -
  • 14:15 (TYS)
    15:09 (ORD)
    4h 14m
    UA 4770 (Embraer RJ145)
    51m layover in Chicago (ORD)
  • 16:00 (ORD)
    17:29 (DSM)
    4h 14m
    UA 4541 (Canadair Regional Jet 700)
  • 14:21 (TYS)
    15:15 (ORD)
    4h 8m
    UA 5533 (Canadair Regional Jet 200)
    45m layover in Chicago (ORD)
  • 16:00 (ORD)
    17:29 (DSM)
    4h 8m
    UA 4541 (Canadair Regional Jet 700)
  • 16:05 (TYS)
    17:12 (CLT)
    6h 9m
    AA 5222 (Canadair Regional Jet 200)
    2h 43m layover in Charlotte (CLT)
  • 19:55 (CLT)
    21:14 (DSM)
    6h 9m
    AA 5085 (Canadair Regional Jet 900)
  • 16:55 (TYS)
    17:51 (ATL)
    4h 51m
    DL 5201 (Canadair Regional Jet)
    1h 39m layover in Atlanta (ATL)
  • 19:30 (ATL)
    20:46 (DSM)
    4h 51m
    DL 3963 (Canadair Regional Jet 900)
  • 17:20 (TYS)
    19:02 (DTW)
    4h 32m
    DL 3689 (Canadair Regional Jet)
    43m layover in Detroit (DTW)
  • 19:45 (DTW)
    20:52 (DSM)
    4h 32m
    DL 3682 (Canadair Regional Jet 900)
  • 17:21 (TYS)
    19:04 (DTW)
    4h 31m
    DL 3764 (Canadair Regional Jet)
    41m layover in Detroit (DTW)
  • 19:45 (DTW)
    20:52 (DSM)
    4h 31m
    DL 3682 (Canadair Regional Jet 900)
  • 17:23 (TYS)
    19:04 (DTW)
    4h 20m
    DL 4607 (Canadair Regional Jet)
    41m layover in Detroit (DTW)
  • 19:45 (DTW)
    20:43 (DSM)
    4h 20m
    DL 3913 (Canadair Regional Jet 900)
  • 17:24 (TYS)
    19:05 (DTW)
    4h 6m
    DL 3891 (Canadair Regional Jet)
    30m layover in Detroit (DTW)
  • 19:35 (DTW)
    20:30 (DSM)
    4h 6m
    DL 3920 (Canadair Regional Jet 900)
  • 17:28 (TYS)
    18:30 (ATL)
    5h 42m
    DL 3449 (Canadair Regional Jet 900)
    2h 15m layover in Atlanta (ATL)
  • 20:45 (ATL)
    22:10 (DSM)
    5h 42m
    DL 1386 (Boeing (Douglas) MD-88)
  • 17:30 (TYS)
    19:13 (DTW)
    4h 22m
    DL 3484 (Canadair Regional Jet)
    32m layover in Detroit (DTW)
  • 19:45 (DTW)
    20:52 (DSM)
    4h 22m
    DL 5552 (Canadair Regional Jet 900)
  • 17:35 (TYS)
    18:24 (ORD)
    3h 51m
    UA 5527 (Canadair Regional Jet 200)
    51m layover in Chicago (ORD)
  • 19:15 (ORD)
    20:26 (DSM)
    3h 51m
    UA 5544 (Canadair Regional Jet 200)
  • 17:35 (TYS)
    18:24 (ORD)
    3h 51m
    UA 5527 (Canadair Regional Jet 700)
    51m layover in Chicago (ORD)
  • 19:15 (ORD)
    20:26 (DSM)
    3h 51m
    UA 3608 (Embraer 170)
  • 17:39 (TYS)
    18:30 (ORD)
    4h 28m
    UA 5527 (Canadair Regional Jet 200)
    1h 6m layover in Chicago (ORD)
  • 19:36 (ORD)
    21:07 (DSM)
    4h 28m
    UA 146 (Airbus A319)
    multiple schedules, see details
    • Valid between 28 Nov 2016 - 18 Dec 2016
      -
      -
    • Valid between 13 Feb 2017 - 05 Mar 2017
  • 17:39 (TYS)
    18:30 (ORD)
    4h 46m
    UA 5527 (Canadair Regional Jet 200)
    1h 30m layover in Chicago (ORD)
  • 20:00 (ORD)
    21:25 (DSM)
    4h 46m
    AA 4711 (Embraer 175)
  • 17:39 (TYS)
    18:30 (ORD)
    4h 27m
    UA 3972 (Embraer RJ 135/140/145)
    1h 5m layover in Chicago (ORD)
  • 19:35 (ORD)
    21:06 (DSM)
    4h 27m
    UA 146 (Airbus A319)
  • 17:45 (TYS)
    18:48 (CLT)
    4h 29m
    AA 5032 (Canadair Regional Jet 900)
    1h 7m layover in Charlotte (CLT)
  • 19:55 (CLT)
    21:14 (DSM)
    4h 29m
    AA 5085 (Canadair Regional Jet 900)
  • 18:45 (TYS)
    20:01 (ATL)
    4h 28m
    DL 779 (Boeing 717-200)
    44m layover in Atlanta (ATL)
  • 20:45 (ATL)
    22:13 (DSM)
    4h 28m
    DL 1386 (Boeing (Douglas) MD-88)
  • 18:45 (TYS)
    19:52 (ATL)
    4h 30m
    DL 5189 (Canadair Regional Jet)
    53m layover in Atlanta (ATL)
  • 20:45 (ATL)
    22:15 (DSM)
    4h 30m
    DL 1386 (Boeing (Douglas) MD-88)
  • 18:45 (TYS)
    19:50 (ATL)
    4h 31m
    DL 5497 (Canadair Regional Jet)
    1h 10m layover in Atlanta (ATL)
  • 21:00 (ATL)
    22:16 (DSM)
    4h 31m
    DL 3963 (Canadair Regional Jet 900)
  • 18:54 (TYS)
    20:01 (ATL)
    4h 21m
    DL 835 (Boeing 717-200)
    49m layover in Atlanta (ATL)
  • 20:50 (ATL)
    22:15 (DSM)
    4h 21m
    DL 1386 (Boeing (Douglas) MD-88)
    multiple schedules, see details
    • Valid between 31 Oct 2016 - 18 Dec 2016
    • Valid between 09 Jan 2017 - 19 Feb 2017
      -

Find cheap airfares for flights from Knoxville to Des Moines. Use gh.wego.com to search and compare low airfare airline tickets for Knoxville to Des Moines flights on various international airlines. FInd last minute flights and the latest low airfares for this route. Compare cheap Knoxville to Des Moines flights at a glance and get the best deal for your trip.

Besides Des Moines flights, find cheap hotels and quality accommodation in Des Moines with Wego. Search and compare Des Moines hotels online to book your ideal travel accommodation.